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1.
The polite way to describe somthing that is "fucked up"
Jack muffed up Jason's face after Jason attempted to finger Jacks mothers asshole while she was sleeping.
od uživatele scott 30. Leden 2004
 
2.
muffed up means fucked up. use "muff" to replace fuck. very fun to use so you dont get in trouble by the parentals or offend the old folks. use different variations of muff too-muffer, muffing, etc.
That's muffed up dude!
Go muff yourself.
od uživatele Kyle Ernesti 16. Červen 2006
 
3.
synonym for fucked up.

slang term that is often used on Call of Duty Modern Warfare 2
Alex: Dude what did Sam do?

Tyler: He cried after getting high

Alex: Thats muffed up
od uživatele Alex Hildenbrand 05. Květen 2010
 
4.
In a way the same as Muff diving, but all over the place.
Damn...you got all muffed up!!!!!
od uživatele iohnoprngs 22. Březen 2009
 
5.
phrase referring to fucking up sex by not shaving your muff
We was about to hit it right, but i reached in, felt that bush and though "damn, this bitch muffed up." She knew she muffed up too.
od uživatele Fisherella 30. Červen 2009